Indian Institute of Technology Guwahati
Department of Biosciences and Bioengineering

Stem Cell and Cancer Biology Group
 

Teaching


Semester (July-Nov 2025)

BT 503 Advanced Genetic Engineering (M.Tech-BT)

Principles of recombinant DNA technology and its applications: identification, isolation, amplification and cloning of genes; High throughput analysis of genome and proteome; Recombinant protein expression systems: design of different expression systems in E.coli, yeast, fungi, plant and mammalian cells; Transgenic plants, animals and their applications; Molecular therapeutics: Gene probes and DNA fingerprinting for diagnosis, identification of biomarkers, gene silencing using antisense and siRNA technology, gene therapy systems, application of stem cells in therapy, recombinant vaccines and antibodies.


HT 501 Introduction to Cellular Processes (M.Tech)

Basics of cell types; structural organization and function of intracellular organelles: nucleus, mitochondria, Golgi bodies, lysosomes, endoplasmic reticulum, peroxisomes, plastids, vacuoles, chloroplasts, structure & function of cytoskeleton and its role in motility; Structure of model membrane, lipid bilayer and membrane protein diffusion, osmosis, ion channels, active transport, membrane pumps, mechanism of sorting and regulation of intracellular transport, electrical properties of membranes; Basics of thermodynamics in bio-systems, common biochemical reactions, phosphorylation and ATP, biological oxidation reduction; Chromosomes and their structure cell division: mitosis and meiosis, steps in cell cycle and its regulation; From gene to protein: DNA replication, transcription/RNA synthesis, and translation/protein synthesis; General principles of cell communication, cell adhesion and roles of different adhesion molecules, gap junctions, extracellular matrix, integrins, neurotransmission and its regulation; Introduction to metabolic pathways: catabolic pathways and anabolic pathways – glycolysis, TCA cycle, fatty acid and amino acid metabolism, metabolic regulation; Hormones and their receptors, cell surface receptor, signalling through G-protein coupled receptors, signal transduction pathways, light signalling in plants, bacterial chemotaxis and quorum sensing; Essential techniques applied in cell biology with case studies, basic of recombinant technology, reporter constructs, and oligonucleotide array.


Courses Taught

Undergraduate courses (B.Tech)
BT 101 Modern Biology
BT 202M Molecular Biotechnology
BT 204 Genetics
BT 208 Molecular Biology and Genetic Engineering
BT 303 Immunology
BT 308 Animal Cell Biotechnology
BT 308 Bioengineering
BT 301M Cellular Biotechnology
BT 312 Analytical Biotechnology Lab

Postgraduate courses (B.Tech, M. Tech and Ph.D)
BT 503 Advanced Genetic Engineering
BT 540 Applied Bioengineering Lab
BT 605 Gene Therapy
BT 632 Stem Cells, Cancer & Therapy
BT 636 Tissue Engineering and Stem Cells
HT 502 Basic Physiology for Clinical Immersion
HT 511 Stem Cells and Therapeutics

Elective courses developed
BT 632 Stem Cells, Cancer & Therapy
BT 637 Genome Editing and Engineering

 
Last updated: 2025